Retinoids Explained

The term "retinoids" refers to vitamin A and the various molecules derived from vitamin A, which itself is also known as retinol (ROL). In the skin, ROL is converted to retinaldehyde (RAL) and then to retinoic acid (RA). Misuse of the terminology has led to much confusion around the whole issue of Vitamin A derivatives and their use.  At the end of the day, it’s only RA (retinoic acid) that modulates gene expression and influences cellular processes in both the epidermis and the dermis, and the path to get there is either indirectly via retinol (the Vitamin A derivative, not to be confused with Vitamin A) or retinaldehyde, or directly with tretinoin (retinoic acid).

Posted on January 9, 2017 .